Publications
Selected landmark and recent work
Explore publications spanning DREAM-complex discovery, cell-cycle repression, quiescence, developmental DYRK1A biology and translational cancer research.
Proteasome inhibition paradoxically degrades gain-of-function mutant p53 R273H in NSCLC and could have therapeutic implications
Frontiers in Oncology
Dyrk1a is required for craniofacial development in Xenopus laevis
Developmental Biology
Insights from the protein interaction Universe of the multifunctional “Goldilocks” kinase DYRK1A
Frontiers in Cell and Developmental Biology
PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis
Molecular Cell
Restoring the DREAM Complex Inhibits the Proliferation of High-Risk HPV Positive Human Cells
Cancers
The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb
Oncogene
A Systematic Analysis of Negative Growth Control Implicates the DREAM Complex in Cancer Cell Dormancy
Molecular Cancer Research
Structural mechanisms of DREAM complex assembly and regulation
Genes & Development
DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly
Genes & Development
Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
Molecular Cell